The purpose of this paper is to address the importance of physiologic imaging for the staging and follow up of patients with breast cancer according to the principles of precision medicine. Precision medicine is the “tailoring of medical treatment to the individual characteristics, needs and preferences of a patient during all stages of care, including prevention, diagnosis, treatment and follow-up.” Currently, physiologic imaging is primarily performed with 18F –FDG- PET/CT, but other tracers are increasingly being used towards the goal of more specific tumor targeting.
Dense breast tissue is common and normal. About 40% of women over the age of 40 years have dense breasts (1). Dense breasts are more common in younger women and the breasts tend to become more replaced by fat as the glands involute after menopause. Dense breast tissue reduces the effectiveness of mammography and increases the risk for developing breast cancer.
HealthDay (2/28, Doheny) reports that research indicates diagnostic mammograms “are catching more” breast “tumors – but the percentage of false alarms is up” as well. The study “used information from six registries maintained by the Breast Cancer Surveillance Consortium, which is funded by the U.S. National Cancer Institute.” HealthDay adds, “The improved cancer detection rate is the important finding here, said” Dr. Debra Monticciolo, chair of the American College of Radiology Commission on Breast Imaging. The findings were published in Radiology.
Aunt Minnie (12/21) reports that “Statlife has received 510(k) clearance from the” FDA “for its DenSeeMammo breast density assessment software.”
Aunt Minnie (12/19) reports, “Black women are more likely to die from breast cancer than white women, and more evidence is needed to determine whether they should be screened for breast cancer differently, according to the US Preventive Services Task Force’s (USPSTF) sixth annual report to Congress.” The report “lists screening for breast cancer in African-American women as an area with ‘key evidence gaps.’”