The Radiology Business Journal (8/7, Walter) reports a study published in Radiotherapy and Oncology found that “early-stage breast cancer survivors treated with whole breast irradiation (WBI) are at a greater risk of developing a secondary cancer than patients treated with accelerated partial breast irradiation (APBI).” Nienke Hoekstra of Erasmus MC Cancer Centre in Rotterdam, Netherlands, wrote, “The use of APBI could eventually halve the lifetime secondary cancer risk.”
HealthImaging (8/7, O'Connor) reports Dutch researchers “utilized a PET tracer to distinguish differences in estrogen receptor (ER) expression in metastatic breast cancer patients” and their findings “may enhance treatment for these patients.” Geke A.P. Hospers, MD, PhD, and colleagues from the University of Groningen, said, “The results showed that approximately 50 percent of the patients had one or more estrogen-receptor negative lesions, while the primary tumor was estrogen-receptor positive.” The study was published in the Journal of Nuclear Medicine.
Aunt Minnie (8/7, Forrest) reports that according to a study published in the August issue of the Journal of Nuclear Medicine, “clinicians can better direct treatment for patients with metastatic breast cancer” by “identifying differences in estrogen receptor (ER) expression through PET imaging with the tracer F-18 fluoroestradiol (FES).” Senior author Dr. Geke Hospers, PhD, from the University of Groningen said in a statement, “We concluded that F-18 FES uptake in both tumor and normal tissue uptake is heterogeneous and influenced by the site of metastasis,” adding, “This heterogeneity of estrogen receptor expression is, therefore, really common, and it likely affects treatment outcome.”
The Cancer Network (8/6, Levitan) reports that researchers have “found that internal mammary chain (IMC) radiation therapy for breast cancer is associated with increased cardiac toxicity, in particular when paired with anthracycline-based chemotherapy.” The findings were published in the British Journal of Cancer.
The Radiology Business Journal (8/3, Slachta) reported that research indicates “radiologists with less than a decade’s worth of experience and lower annual reading volumes are more likely than their colleagues to have higher mammography recall rates.” The findings were published in the Journal of the American College of Radiology.