Aunt Minnie (4/6) reports an analysis of studies showed that adding digital breast tomosynthesis to full-field digital mammography yields a “higher overall cancer detection rate that was statistically significant.” One author of the analysis, Julie Glanville from the University of York in the UK, said the review was novel in examining DBT versus FFDM for screening, rather than diagnosis. Glanville also said the amount of data was significant, adding, “Very often we are analyzing one or two small studies and it is difficult to draw conclusions, but that was not the case with this review. As far as we are aware, this is the first systematic review of tomosynthesis to be published.”
Aunt Minnie (4/6) reports a study conducted since 2008 by the Ain Shams University in Cairo has found that risk for breast cancer among Egyptian women studied increased as breast density classification increased. Researchers split “136,833 women ranging in age from 40 to 65” into four groups according to ACR mammographic density guidelines: “class A, almost entirely fatty; class B, scattered fibroglandular tissue; class C, heterogeneously dense; and class D, extremely dense.” According to lead researcher Dr. Nivine Chalabi, there was a “statistically highly significant” rise in risk between class A and class B, as well as between any two ascending groups.
According to Diagnostic Imaging (4/4), a new study published in Radiology found that “MRI may help predict recurrence-free survival (RFS) in women with breast cancer, even in the presence of pathologic complete response (PCR) and residual cancer burden (RCB) class.”